Mild encephalitis/encephalopathy with a reversible splenial lesion in children.
Identifieur interne : 001F38 ( Main/Exploration ); précédent : 001F37; suivant : 001F39Mild encephalitis/encephalopathy with a reversible splenial lesion in children.
Auteurs : Zoltán Liptai [Hongrie] ; Balázs Ivády ; Péter Barsi ; György Várallyay ; Gábor Rudas ; András FogarasiSource :
- Ideggyogyaszati szemle [ 0019-1442 ] ; 2013.
Descripteurs français
- KwdFr :
- Accident ischémique transitoire (anatomopathologie), Accident ischémique transitoire (étiologie), Acide acétylsalicylique (administration et posologie), Adolescent, Angiographie par résonance magnétique, Anti-inflammatoires (administration et posologie), Antipyrétiques (administration et posologie), Corps calleux (anatomopathologie), Diurétiques osmotiques (administration et posologie), Encéphale (anatomopathologie), Encéphalite (), Encéphalite (anatomopathologie), Encéphalite (diagnostic), Encéphalite (traitement médicamenteux), Encéphalite virale (diagnostic), Enfant, Femelle, Humains, Imagerie par résonance magnétique, Mannitol (administration et posologie), Méthylprednisolone (administration et posologie), Neuroprotecteurs (administration et posologie), Oedème cérébral (anatomopathologie), Oedème cérébral (étiologie), Résultat thérapeutique.
- MESH :
- administration et posologie : Acide acétylsalicylique, Anti-inflammatoires, Antipyrétiques, Diurétiques osmotiques, Mannitol, Méthylprednisolone, Neuroprotecteurs.
- anatomopathologie : Accident ischémique transitoire, Corps calleux, Encéphale, Encéphalite, Oedème cérébral.
- diagnostic : Encéphalite, Encéphalite virale.
- traitement médicamenteux : Encéphalite.
- étiologie : Accident ischémique transitoire, Oedème cérébral.
- Adolescent, Angiographie par résonance magnétique, Encéphalite, Enfant, Femelle, Humains, Imagerie par résonance magnétique, Résultat thérapeutique.
English descriptors
- KwdEn :
- Adolescent, Anti-Inflammatory Agents (administration & dosage), Antipyretics (administration & dosage), Aspirin (administration & dosage), Brain (pathology), Brain Edema (etiology), Brain Edema (pathology), Child, Corpus Callosum (pathology), Diuretics, Osmotic (administration & dosage), Encephalitis (complications), Encephalitis (diagnosis), Encephalitis (drug therapy), Encephalitis (pathology), Encephalitis, Viral (diagnosis), Female, Humans, Ischemic Attack, Transient (etiology), Ischemic Attack, Transient (pathology), Magnetic Resonance Angiography, Magnetic Resonance Imaging, Mannitol (administration & dosage), Methylprednisolone (administration & dosage), Neuroprotective Agents (administration & dosage), Treatment Outcome.
- MESH :
- chemical , administration & dosage : Anti-Inflammatory Agents, Antipyretics, Aspirin, Diuretics, Osmotic, Mannitol, Methylprednisolone, Neuroprotective Agents.
- complications : Encephalitis.
- diagnosis : Encephalitis, Encephalitis, Viral.
- drug therapy : Encephalitis.
- etiology : Brain Edema, Ischemic Attack, Transient.
- pathology : Brain, Brain Edema, Corpus Callosum, Encephalitis, Ischemic Attack, Transient.
- Adolescent, Child, Female, Humans, Magnetic Resonance Angiography, Magnetic Resonance Imaging, Treatment Outcome.
Abstract
Authors, most of them Japanese, have recently published an increasing number of articles on mild encephalitis/encephalopathy with a reversible splenial lesion. We report on two new white European patients and compare published data with our own observations. A 15-year-old girl developed headache, fever, dizziness, vomiting and nuchal rigidity over four days. CSF showed elevated protein and cell count, with the lowest serum Na being 131 mmol/L. MRI on day seven was normal, but she remained febrile, had cerebral edema and episodes of confusion. MRI on day 11 showed a small T2-hyperintense lesion with restricted diffusion in the callosal splenium. Adenoviral infection was proved, and the girl underwent a protracted course of recovery. MRI signal changes improved in six days and disappeared after four months. A 12.5-year-old girl developed headache, lethargy, drowsiness and vomiting. On day five she experienced right-sided numbness, weakness and inability to speak which lasted 12 hours. She was confused and disoriented. MRI disclosed a tiny area of increased T2-signal and restricted diffusion in the splenium. Serum Na was 133 mmol/L, CSF cell count and protein was markedly elevated, and enteroviral infection was detected. Echocardiography showed no changes predisposing to clot formation and no thrombophilia was found. Her symptoms resolved in a week and MRI was normal two months later. These two non-epileptic children increase the small number of white European patients with MERS reported so far. Both had hyponatremia and encephalitis and patient 2 had transient ischemic attack, possibly due to the cerebral edema also resulting in the splenial lesion.
PubMed: 23607233
Affiliations:
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type="abstract" xml:lang="en">Authors, most of them Japanese, have recently published an increasing number of articles on mild encephalitis/encephalopathy with a reversible splenial lesion. We report on two new white European patients and compare published data with our own observations. A 15-year-old girl developed headache, fever, dizziness, vomiting and nuchal rigidity over four days. CSF showed elevated protein and cell count, with the lowest serum Na being 131 mmol/L. MRI on day seven was normal, but she remained febrile, had cerebral edema and episodes of confusion. MRI on day 11 showed a small T2-hyperintense lesion with restricted diffusion in the callosal splenium. Adenoviral infection was proved, and the girl underwent a protracted course of recovery. MRI signal changes improved in six days and disappeared after four months. A 12.5-year-old girl developed headache, lethargy, drowsiness and vomiting. On day five she experienced right-sided numbness, weakness and inability to speak which lasted 12 hours. She was confused and disoriented. MRI disclosed a tiny area of increased T2-signal and restricted diffusion in the splenium. Serum Na was 133 mmol/L, CSF cell count and protein was markedly elevated, and enteroviral infection was detected. Echocardiography showed no changes predisposing to clot formation and no thrombophilia was found. Her symptoms resolved in a week and MRI was normal two months later. These two non-epileptic children increase the small number of white European patients with MERS reported so far. Both had hyponatremia and encephalitis and patient 2 had transient ischemic attack, possibly due to the cerebral edema also resulting in the splenial lesion.</div></front></TEI><affiliations><list><country><li>Hongrie</li></country><region><li>Hongrie centrale</li></region><settlement><li>Budapest</li></settlement></list><tree><noCountry><name sortKey="Barsi, Peter" sort="Barsi, Peter" uniqKey="Barsi P" first="Péter" last="Barsi">Péter Barsi</name><name sortKey="Fogarasi, Andras" sort="Fogarasi, Andras" uniqKey="Fogarasi A" first="András" last="Fogarasi">András Fogarasi</name><name sortKey="Ivady, Balazs" sort="Ivady, Balazs" uniqKey="Ivady B" first="Balázs" last="Ivády">Balázs Ivády</name><name sortKey="Rudas, Gabor" sort="Rudas, Gabor" uniqKey="Rudas G" first="Gábor" last="Rudas">Gábor Rudas</name><name sortKey="Varallyay, Gyorgy" sort="Varallyay, Gyorgy" uniqKey="Varallyay G" first="György" last="Várallyay">György Várallyay</name></noCountry><country name="Hongrie"><region name="Hongrie centrale"><name sortKey="Liptai, Zoltan" sort="Liptai, Zoltan" uniqKey="Liptai Z" first="Zoltán" last="Liptai">Zoltán Liptai</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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